Dear students, faculty, alumni, staff, and friends,
School publications such as this newsletter and our most recent annual report give me the opportunity to reflect proudly upon the school's many accomplishments across its mission-critical areas of education, research and service. As we end the quarter and prepare for the holidays, I hope you take time to reflect upon the ways in which you have contributed to the school's success. We reached many high points during FY 07-08, conducting more than 160,000 patient visits and breaking the "top five" of educational institutions supported by the National Institutes of Dental and Craniofacial Research. Of course, there are more goals to reach and obstacles to overcome in the year ahead, and I encourage you to think about the crucial part you will play. It is clear to me that while we are in the midst of a challenging time for the country, the state and the University of California, we nevertheless have many strengths upon which to draw and much to celebrate. Please join me in doing so.
Happy holidays!
Dean No-Hee Park, D.M.D, Ph.D.
On October 22, 2008 dental and medical school faculty, members of the Jonsson Cancer Center, staff and students gathered for the UCLA School of Dentistry's inaugural research day, the theme of which was "Basic and Translational Research in Oral/Head and Neck Cancer." Dr. Waun Ki Hong of M.D. Anderson Cancer Center, a leading authority on head, neck and lung cancers and one of the founders of cancer chemoprevention, delivered a well-received keynote address.
Another highlight of the event program was the faculty symposium moderated by Dr. Anahid Jewett. Drs. David Wong, Cun-Yu Wang, Ren Sun and Mo Kang presented their research, demonstrating the many ways in which UCLA is leading the field of 21st Century dental medicine by advancing the science of salivary diagnostics, fighting oral cancer and the herpes virus, and finding new ways to control the side effects of oral cancer treatment.
A poster competition for dental students and residents brought the day to its successful conclusion with 29 entrants presenting their research. In the predoctoral category, Aasia Rehman (mentor: Dr. Cun-Yu Wang) took first place;
Shaoying Lee (mentors: Drs. Hongyu Deng & Ren Sun) took second place, and
Anna Kreymer (mentor: Dr. Susan Haake) took third place honors. In the
postdoctoral category,
Eric Tang (mentor: Dr. Cun-Yu Wang)
placed first; Akishige Hokugo (mentor: Dr. Ichiro Nishimura)
placed second, and third place went to Cristiane Mengatto (mentor: Dr. Ichiro Nishimura). Congratulations to all the winners! Click here for a poster competition slideshow, and
here for more information about research day.
Dr. David Wong, a pioneer in the burgeoning field of salivary diagnostics--the science of using saliva rather than blood or other bodily fluids to diagnose disease--will hold the Felix and Mildred Yip Endowed Professorship in Dentistry effective January 1, 2009.
“I am immensely honored and grateful to Dr. and Mrs. Yip and to the UCLA School of Dentistry,” said Dr. Wong, associate dean of research and director of the Dental Research Institute. “This chair will allow me and my research team to continue to spearhead salivary diagnostics to transform clinical practice in the years ahead.”
The new endowed professorship was established through the generosity of Dr. Felix and Mrs. Mildred Yip, noted philanthropists within the Asian American community in Southern California who have been generous supporters of UCLA and the School of Dentistry.
Click here to read the full press release announcing the new chair. Click here to watch a video about the saliva test for oral cancer.
Did you know that 42 percent of Americans age 65 and older are totally edentulous (they have no teeth)? Or that Americans lose an average of 12 teeth by the age of 50? These are the prospective patients Dr. Tak Ogawa had in mind when he set out to improve dental implants, a therapeutic alternative that until now has been beyond the practical and financial reach of many people who could benefit from it. Fortunately, dental implants may be more accessible in the future, not to mention stronger, faster and more "doctor-friendly," thanks to Dr. Ogawa's research. In fact, his techniques (which can be implemented singly or synergistically) may make 100 percent bone-to-implant connection a reality for the very first time (see photo above for what Dr. Ogawa has trademarked as "superosseointegration").
Dr. Ogawa has hit upon two distinct ways to improve implant therapy which have attracted the notice of a commercial enterprise with plans to make at least one of the new technologies clinically available in early 2010. Dr. Ogawa has found that UV light can be used to treat the titanium surface of implants, rendering them more "bioactive"--more likely to attract proteins and bone-making cells and thereby improve implant retention at a faster pace, speeding patient recovery.
He also has created a patented chemical reaction to deposit evaporated titanium on implant surfaces which gives rise to nano-sized hemispherical structures (see b&w photo at left) that increase surface area and bonding potential. Both innovations promise to accelerate the implant treatment cycle and, according to Dr. Ogawa, could increase the number of implant surgeries performed in this county from the current one billion annually to two billion per year within the next five years. And, as Dr. Ogawa points out, more surgeries performed will lead to greater economies of scale, lowering the cost of treatment. The innovations also hold promise for other applications of orthopedic implants and tissue engineering for wound healing.
Read the latest issue of UCLA Invents to learn more about Dr. Ogawa's innovations and other UCLA research efforts attracting the attention of the investment community.
Tara Aghaloo has won a $52,000 grant from Medtronic to study the effects of Bone Morphogenetic Protein-2 (BMP-2) and Platelet-Derived Growth Factor (PDGF) on ectopic bone formation in rats.
James Crall has won more than $66,000 in funding to partner with the USC School of Dentistry in planning an "Oral Health Baseline Needs Assessment Project" focusing on children in Los Angeles County. The project is funded by the California Endowment, FIRST 5 LA, the California Wellness Foundation and the Annenberg Foundation.
The NIH/NIDCR has awarded Diana Messadi an R25 Oral Health Research Education Grant of more than $647,000 for her work recruiting, mentoring, and empowering the next generation of academic dentists.
Francisco Ramos-Gomez, who joined the faculty in March 2008, has transferred to UCLA more than $600,000 in funding in the form of two NIH/NIDCR awards: an R01 component of a U54 grant for the "Center to Address Disparities in Children's Oral Health" and an R21 Exploratory/Developmental Research Grant for the "San Francisco Maternal and Child Oral Health 'PRIME' Project."
Cun-Yu Wang has won a $1.5 Million NIH/NIDCR R01 grant for his research investigating how immune cytokines promote oral bone loss through IkB kinase.
The NIH/NCI has awarded $1.7 Million in R01 funding to David Wong for the study of the molecular determinants of oral tongue cancer metastasis. Wong also received $75,000 from the IADR and Glaxo SmithKline for "SPITDX: A Universal Platform for Salivary Biomarker Detection." In addition, the NIH/NIDCR renewed the school's T32 training grant for an additional four-year period. The grant, in the amount of $2.7 Million, funds the "UCLA Dentist-Scientist & Oral Health Scientist Training Program." Wong serves as director of the program.