Bo    Yu, D.D.S., Ph.D.
Assistant Professor
Phone:
(310) 825-8026
Address:
UCLA School of Dentistry
10833 Le Conte Ave.
Box 951668
Los Angeles, CA 90095-1668
Office:  CHS 43-091

Biography

Bo Yu, D.D.S., Ph.D. is an Assistant Professor in the Section of Restorative Dentistry, Division of Constitutive & Regenerative Sciences. 

Educational & Professional Background

  • Ph.D. in Oral Biology, UCLA School of Dentistry, 2014

  • D.D.S., UCLA School of Dentistry, 2011

Research & Interests

Dr Yu’s research interests lie in bone biology and stem cell-mediated regeneration. Previous and ongoing work focus on: 1) the molecular interactions between inflammation and bone metabolism in systemic and craniofacial bone diseases such as osteoporosis and periodontitis; 2) epigenetic regulation of stem cell differentiation and cell fate determination.  

Professional Memberships

  • International Association of Dental Research

  • American Association of Dental Research

  • California Dental Association

Representative Publications

  1. Yu B, Wang CY. Osteoporosis, a result of an “aged” bone microenvironment. Trends in Molecular Medicine. (In review)

  2. Park HW, Kim YC, Yu B, Moroishi T, Mo J, Plouffe S, Meng Z, Lin KC, Yu FX, Alexander CM, Wang CY, Guan KL. Alternative Wnt signaling activates YAP/TAZ. Cell. 162(4):780-94. 2015.

  3. Yu B*, Chang J, Liu Y, Li J, Kevork K, Al-Hezami K, Graves DT, Park NH, Wang CY. Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB. Nature Medicine,20(9):1009-17. 2014. *Co-first author

  4. Ye L, Fan Z, Yu B*, Chang J, Al Hezaimi K, Zhou X, Park NH, Wang CY. Histone demethylases KDM4B and KDM6B promotes osteogenic differentiation of human MSCs. Cell Stem Cell, 11(1):50-61, 2012. *Co-first author

Additional Information

Teaching Activities

RFE 101 Dental Waxing

RFE 202 Conservative Direct Restorations

RFE 105 Clinical Applications of Dental Morphology and Occlusion

CL402.02b Restorative Dental Clinic supervision and Treatment Planning