Shen  Hu, Ph.D., M.B.A
Professor
Phone:
(310) 206-8834
Address:
UCLA School of Dentistry
10833 Le Conte Ave.
Box 951668
Los Angeles, CA 90095-1668
Office:  63-070 CHS

Biography

Dr. Hu is a Professor and the MS Program Advisor in the Division of Oral Biology and Medicine at the UCLA School of Dentistry. He joined the Division of Oral Biology and Medicine in 2003. 

Educational & Professional Background

  • Ph.D., Wuhan University, 1996

  • Research Fellow, City University of Hong Kong, 1997

  • Postdoctoral Fellow, University of Alberta, 2000

  • Research Assistant Professor, University of Washington, 2003

  • M.B.A, UCLA Anderson School of Management, 2016 

Research & Interests

  • Cancer metabolomics/proteomics

  • Cancer stem cells

  • Sjogren’s syndrome

  • Burning mouth syndrome and chronic pain

Professional Memberships

  • Full Member, UCLA Jonsson Comprehensive Cancer Center

  • Editorial Board Member, American Journal of Stem Cells

  • Associated Editor, Journal of Integrated Omics

  • Editorial Board Member, Oral Health and Dental Management

  • Editorial Board Member, International Journal of Analytical Mass Spectrometry and Chromatography

  • Editorial Board Member, Current Metabolomics

  • Editorial Board Member, Research In Cancer and Tumor

  • Editorial Board Member, Proteomics Insights Journal

  • Editorial Board Member, Open Proteomics Journal

  • Editorial Board Member, Open Journal of Biochemistry

Awards

  • Sjogren’s Syndrome Foundation Research Grant (PI)

  • UCLA Faculty Research Grant (PI)

  • Sichuan Medical Council Oral Cancer Research Grant (PI)

  • Wendy Will Case Cancer Fund (PI)

  • Hirshberg Pancreatic Cancer Foundation Faculty Award (PI)

  • TRDRP Exploratory/Developmental Grant (PI)

  • American Recovery & Reinvestment Act Student Grant, R21CA122806S1 (PI)

  • American Recovery & Reinvestment Act Student Grant, R03DE01714402S1 (PI)

  • UCLA Pathology/Dentistry Research Service Award (PI)

  • UC CRCC Cancer Research Award (PI)

  • NIH/NCI R21 CA122806 Award (PI)

  • NIH/NIDCR R03 DE017144 Award (PI)

  • NIH/NIDCR R01DE017593 (Co-PI)

Representative Publications

  • Zhang X, Zhou Q, Shen Z, Li Z, Fei R, Ji EH, Hu S*, Hu Y.  Quantum dot incorporated Bacillus spore as nanosensor for viral infection. Biosens Bioelectron. 2015;74:575-80.

  • Hu S, Wang J, Ji EH, Christison T, Lopez L, Huang Y. Targeted Metabolomic Analysis of Head and Neck Cancer Cells Using High Performance Ion Chromatography Coupled with a Q Exactive HF Mass Spectrometer. Anal Chem. 2015;87(12):6371-9.

  • Wang J, Christison TT, Misuno K, Lopez L, Huhmer AF, Huang Y, Hu S. Metabolomic profiling of anionic metabolites in head and neck cancer cells by capillary ion chromatography with Orbitrap mass spectrometry. Anal Chem. 2014;86(10):5116-24.

  • Misuno K, Liu X, Feng S, Hu S. Quantitative proteomic analysis of sphere-forming stem-like oral cancer cells. Stem Cell Res Ther. 2013;4(6):156.

  • Chai YD, Zhang L, Yang Y, Su T, Charugundla P, Ai J, Messadi D, Wong DT, Hu S. Discovery of potential serum protein biomarkers for lymph node metastasis in oral cancer. Head Neck. 2016;38(1):118-25.

  • Arellano-Garcia ME, Misuno K, Tran SD, Hu S. Interferon-γ induces immunoproteasomes and the presentation of MHC I-associated peptides on human salivary gland cells. PLoS One. 2014;9(8):e102878.

  • Fang D, Hu S, Liu Y, Quan VH, Seuntjens J, Tran SD. Identification of the active components in Bone Marrow Soup: a mitigator against irradiation-injury to salivary glands. Sci Rep. 2015;5:16017.

  • Misuno K, Tran SD, Khalili S, Huang J, Liu Y, Hu S. Quantitative analysis of protein and gene expression in salivary glands of Sjogren's-like disease NOD mice treated by bone marrow soup. PLoS One. 2014;9(1):e87158.

Additional Information

Courses Taught
  • System-Based Healthcare 2015-2016 (course instructor, UCLA Medical/Dental)

  • OB208, Genomics and Proteomics in Oral Biology (2010-present, Course Chair)

  • OB201C, Advanced Oral Pathobiology (2014-present, Course Chair)

  • OB201C, Advanced Oral Pathobiology (2005-2013, course instructor)

  • OB260, Current Research in Oral Biology (2006-2007, course Co-Chair and Chair)

  • OB212, Proseminar: Oral Biology Research (course lectures)

  • OB 275, Mol Cell Biology (2005, 2008, course lectures)