Yong Kim, Ph.D.
Professor-in-Residence
Phone:
(310) 825-7210
Address:
UCLA School of Dentistry
10833 Le Conte Ave.
Box 951668
Los Angeles, CA 90095-1668
Office:  73-022 CHS

Biography

Yong Kim, Ph.D. is a Professor-in-Residence in the Section of Oral Biology in the Division of Oral Biology & Medicine at the UCLA School of Dentistry. He is also a member of UCLA’s Jonsson Comprehensive Cancer Center and UCLA Broad Stem Cell Research Institute.

Educational & Professional Background

  • B.S. Chemistry, Seoul National University, Seoul, Rep of Korea, 1985
  • M.S. Biochemistry & Molecular Biology, Mississippi State University, 1992
  • M.S. Biochemistry, University of Rochester, 1993
  • Ph.D. Biochemistry, University of Rochester,1998

Research & Interests

  • Study on the cellular and molecular function of cell cycle regulator in embryonic stem cell differentiation and embryo development.

  • Molecular determinants in the effects of teratogen in human stem cells.

  • Epigenetic regulation in embryonic stem cell differentiation and cancer development.

  • Role of CDK2AP1 in cell cycle regulation and the significance of its differential expression in cellular transformation in relation to checkpoint regulation and apoptosis.

  • Translational application of cell cycle regulatory mechanism for head and neck/oral cancer treatment.

  • Liquid biopsy for cancer detection using cancer-associated oncogenic mutations

Professional Memberships

  • American Association for Cancer Research: Associate member since 1998.

  • American Association for the Advancement of Science: member since 2000.

  • International Association for Dental Research: member since 2002.

  • International Society for Stem Cell Research: member since 2011.

  • Research Society on Alcoholism: member since 2018.

Awards

  • California Institute of Regenerative Medicine Basic Biology Award
  • R01 NIH/NIAAA
  • R21 NIH/NIAAA
  • UH2/UH3 NIH/NCATS
  • UG3/UH3 NIH/NCATS
  • TRDRP
  • JCCC SEED Fund

Representative Publications

Li, F., Wei, F., Huang, W.-L., Lin, C.-C., Li, L., Shen, M., Yan, Q., Liao, W., Chia, D., Tu, M., Tang, J., Feng, Z., Kim, Y., Su, W.-C., David Wong, D. Ultra-Short Circulating Tumor DNA (usctDNA) in Plasma and Saliva of Non-Small Cell Lung Cancer (NSCLC) Patients. (2020). Cancers 12(8), 2041

Kaczor-Urbanowicz, K.E., Cheng, J., King, J.C., Sedarat, A., Pandol, S.J., Farrell, J., Wong, D.T.W., and Kim, Y. Reviews on current liquid biopsy for detection and management of pancreatic cancers. (2020). Pancreas (In Press).

Wang, Z., Li, F., Rufo, J., Chen, C., Yang, S., Li, L., Zhang, J, Kim, Y., Wu, M., Abemayor, E., Tu, M., Chia, D., Cheng, J., Spruce, R., Batis, N., Mehanna, H., T.W. Wong, D. T. W., and Huang. T. J. Acoustofluidic Salivary Exosome Isolation: A Liquid Biopsy Compatible Approach for Human Papillomavirus-Associated Oropharyngeal Cancer Detection. (2020). Journal of Molecular Diagnostics 22:50-59.

Kaczor-Urbanowicz, K. E., Wei, F., Rao, S. L., Kim, J., Shin, H., Cheng, J., Tu, M., D. T. W., and Kim, Y. Clinical validity of saliva and novel technology for cancer detection. (2019). BBA Reviews on Cancer 1872:49-59.

Das S. et al. The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research. (2019). Cell 177:231-242

Li, F., Yoshizawa, J.M., Kim, K.-M., Kanjanapangka, J., Grogan, T.R., Wang, X., Elashoff, D., Ishikawa, S., Chia, D., Akin, D., Yan, X., Lee, M.-S., Kang. S.-Y., Bae, J.-M., Sohn, T.-S., Lee, J.-H., Choi, M.-G., Min, B.-H., Lee, J.-H., Kim, J.-J., Kim, Y., Kim, S., Wong, D.T.W. (Co-corresponding author). Discovery and Validation of Salivary Extracellular RNA (exRNA) Biomarkers and Panel for Noninvasive Detection of Gastric Cancer. (2018). Clin. Chem. 64(10):1513-1521

Kim, Y.Y., Roubal, I., Lee, Y.S., Kim, J.S., Hoang, M., Mathiyakom, N., and Kim, Y. Alcohol-induced molecular dysregulation in human embryonic stem cell-derived neural precursor cells. (2016). PLoS ONE 11(9):e0163812.

Hoang,M., Kim, J.J., Kim, Y.Y., Tong,E., Trammell,B., Liu, Y., Shi, S., Yang, J., Hong, C., Wang, C.-Y., and Kim, Y. Alcohol-induced suppression of KDM6B dysregulates the mineralization potential in dental pulp stem cells. (2016). Stem Cell Research 17:111-121.

Liu, Y., Kou, X., Chen, C., Yu, J., Su, Y., Kim, Y., Shi, S., and Liu, Y. Chronic High Dose Alcohol Induces Osteopenia via Activation of mTOR Signaling in Bone Marrow Mesenchymal Stem Cells. (2016). Stem Cells 34(6):2157-68.

Cass, A., Bahn, J.H., Lee, J.-H., Greer, C., Lin, X., Kim, Y., Hsiao, Y.-H., Xiao, X. Global analyses of endonucleolytic cleavage in mammals reveal expanded repertoires of cleavage-inducing small RNAs and their targets (2016). Nucleic Acid Research 44(7):3253-3263.

 

Dr. Yong Kim's Google Scholar link

Dr. Yong Kim's Research Gate link

Additional Information

Courses taught
  • OB260 Oral Biology Seminar

  • OB201C Advanced Oral Pathobiology

  • OB275 Molecular and Cellular Biology

  • OSD211 Systems 5

  • OSD201 Block 2