Clinical Trials

WOULD YOU LIKE TO TRY A NEW ELECTRONIC TOOTHBRUSH?

Researchers at the UCLA School of Dentistry are interested in your user experiences with a new electronic toothbrush system over a 4-week period. The system includes an Oral-B Genius 9000 Toothbrush, wearable wrist sensors, and a smart phone app to record your oral health behaviors.

In order to participate, you will be required to do the following during the duration of the study:

  • Allow your brushing and flossing details to be recorded

  • Carry a study-provided smart phone

  • Wear the provided wrist sensors

  • Respond to brief text message surveys

  • Visit our lab twice to undergo training and debriefing

Participants who complete the study will receive up to $140 and keep the Genius Toothbrush.

If you are interested in participating, or would like more information, please contact Cesar Olmos at (626) 775-7995 or UCLAROBAS@gmail.com.

Principal Investigator: Dr. Vivek Shetty, UCLA School of Dentistry, Research supported by the National Institutes of Health.


DO YOU HAVE A TOOTH IN THE FRONT OR MIDDLE OF YOUR UPPER OR LOWER JAW THAT NEEDS TO BE REMOVED?

You may qualify for a research study in the UCLA Dental Implant Center that will evaluate the long-term healing of dental implants. 

Purpose? To evaluate bone and gum healing after placement of a dental implant that is placed at the time of tooth removal as compared to a dental implant placed after healing of an extraction site.

Why? Implants are often placed at the time of tooth removal to decrease treatment time and allow for less surgical procedures. However, conventional dental implants are placed after the tooth is extracted and allowed to heal for several months. Very few direct comparative studies are available to see if there are any differences in these two treatment protocols. In this study, an FDA approved dental implant that is tapered to provide improved stability in the bone if placed at the time of tooth removal will be evaluated and compared to the same implant placed after the tooth extraction site has healed.

What to expect? Volunteers of 20 years of age or older, with overall good medical and dental health, and with at least one tooth in the front or middle of the upper or lower jaw that needs to be extracted may be eligible to participate in this study.

Consultation for research eligibility and if accepted, initial dental and implant examinations; including implant and crown placement. Procedure will be followed by 6 follow-up appointments, the last two at 4 and 5 years, to evaluate healing around the implant.

You may receive $300 payment for your involvement. You will also receive CT scans and 2 dental cleanings at no cost, and a discount on the implant and crown.

For information or to make an appointment contact Dr. Aghaloo in UCLA’s Dental Implant Center: (310) 206-6620, or visit us in UCLA’s Dental Implant Center, UCLA School of Dentistry, B0-129

MONDAY - FRIDAY, 8:00 a.m. - 5:00 p.m.

ALL APPOINTMENTS WILL BE CONDUCTED IN UCLA’s DENTAL IMPLANT CENTER

IRB Flier with approval


DO YOUR GUMS BLEED WHEN YOU BRUSH OR FLOSS ?   DO YOU HAVE “GUM DISEASE”  . . . .  PERIODONTITIS    

If so, you may qualify to participate in a research study at the UCLA Postgraduate Periodontics and Implant Surgery Clinic to evaluate the effectiveness of laser therapy in the treatment of chronic periodontal disease.

Purpose: Laser periodontal therapyis a new treatment that may reduce the need for gum surgery. The purpose of this study is to evaluate the effectiveness of laser therapy, as an adjunct to scaling and root planing (deep cleaning), by comparing it to scaling and root planing alone in the treatment of gum disease. The laser (Biolase iPlus) to be used in this study is approved and available for purchase in the United States; it is currently being used in practice for the treatment of periodontal disease.

HOW CAN I PARTICIPATE IN THIS STUDY?

Screening: You will need a complete clinical and radiographic examination to assess your current periodontal condition and to determine your eligibility for participation. You need to bring (or pay for) initial screening radiographs. The screening exam is free.

Requirements: In order to participate in this study, you must be 25 years old or older (male or female), in generally fair to good health without any diseases or medications that adversely affect healing. Women cannot be pregnant and should not have plans to become pregnant. You should not have any recent (past six months) periodontal “gum” treatment and should not have taken antibiotics in the last six months. Qualifying participants will have at least two teeth with probing pocket depth ≥ 5 mm and interproximal bone loss in two or more quadrants.

Expectations: If you take part in this study, you will receive a comprehensive periodontal examination including all study-related radiographic imaging and non-surgical treatment (scaling and root planing with and without laser therapy) as well as follow up exams and cleanings every three months for twelve months. Following the initial therapy and one week check, you will be expected to return for 5-6 post-treatment exam visits (at 1, 3, 6, 9 and 12 months). Two of these visits (6 and 12 months) will include getting radiographic imaging in the UCLA Oral Radiology Clinic.

Participants who meet the study criteria will receive patient education, non-surgical treatment (with and without laser therapy) and study-related radiographs at no cost. They will be asked to return for follow-up evaluations at 1, 3, 6, 9 and 12 months after treatment. Those who complete all follow-up visits will be compensated $100.00 cash.

Summary: This research study seeks individuals with gum disease (periodontitis) to participate in a clinical study to evaluate the effectiveness of laser therapy in the non-surgical treatment of chronic periodontal disease. Participants will be followed for twelve months. All visits will take place at the UCLA School of Dentistry in the Postgraduate Periodontics and Implant Surgery Clinic.

If you are interested and would like to be screened for participation in this laser therapy study to treat gum disease, please contact Principal Investigator, Dr. Perry Klokkevold, at: (310) 825-3795 or perio_implant@dentistry.ucla.edu