Zhong  Zheng, Ph.D.
Adjunct Assistant Professor
Phone:
(310) 206-5646
Address:
UCLA School of Dentistry
10833 Le Conte Ave.
Box 951668
Los Angeles, CA 90095-1668
Office:  2641-MRL/30-121 CHS

Biography

Zhong Zheng, Ph.D. has also been extensively engaged in research on developing functional biomaterials for tissue engineering, such as using silver nanoparticle-based materials to improve orthopaedic surgeries. During 12 years of using fibromodulin (FMOD) to manage cutaneous wound healing, he was the first person to generate the FMOD-related peptide to reduce scar formation. Recently, Dr. Zheng is focused on developing cell-based regenerative medicines for musculoskeletal tissue engineering. He is the first person that established a novel, technically undemanding FMOD-based approach to reprogram somatic cells without any genetic modifications. Currently, Dr. Zheng is an editor of Oral health and Dental Management and also serves as an active reviewer for many other scientific journals such as Biomaterials, Metabolic Engineering, Tissue Engineering, the Journal of Biomedical Materials Research, Part A, and the African Journal of Biotechnology.

Educational & Professional Background

  • B.S., Tsinghua University, P.R. China., 2001
  • M.S., Ph.D., Tsinghua University, P.R. China., 2005
  • Research Associate, University of Southern California, 2006-2008
  • Postdoctoral Employee, UCLA, 2008-2012

Research & Interests

  • Biomaterials
  • Microbiology
  • Nano-materials
  • Nanotechnologies
  • Regeneration Medicine
  • Stem Cell
  • Tissue Engineering

Professional Memberships

  • Wound healing Society
  • American Society for Bone and Mineral Research

Awards

  • International Health Professional of the Year, 2007
  • DuPond Scholarship, 2004
  • Guang-Hua Scholarship, 2003

Representative Publications

  • Z. Zheng, J. Jian, X. Zhang, J. N. Zara, W. Yin, M. Chiang, Y. Liu, J. Wang, S. Pang, K. Ting, and C. Soo. “Reprogramming of human fibroblasts into multipotent cells with a single extracellular matrix proteoglycan, fibromodulin.” Biomaterials 33: 5821-5831. (2012)
  • Z. Zheng, C. Nguyen, X. Zhang, H. Khorasani, J.Z. Wang, J.N. Zara, F. Chu, W. Yin, P. Shen, A. Le, K. Ting, and C. Soo. “Delayed wound closure in fibromodulin deficient mice is associated with increased TGF-b3 signaling.” Journal of Investigative Dermatology 131: 769-778. (2011)
  • Z. Zheng, W. Yin, J.N. Zara, W. Li, J. Kwak, R. Mamidi, M. Lee, R.K. Siu, R. Ngo, J. Wang, D. Carpenter, X. Zhang, B. Wu, K. Ting, and C. Soo. “The use of BMP-2 coupled-nanosilver-PLGA composite grafts to induce bone repair in grossly infected segmental defects.” Biomaterials 31 (35): 9293-9300. (2010)
  • Z. Zheng, F. Bei, H. Tian, and G.Q. Chen. “Effect of crystallization of polyhydroxyalkanoate blend on surface physicochemical properties and interactions with rabbit articular cartilage chondrocytes.” Biomaterials 26 (17): 3537-3548. (2005)
  • Z. Zheng, Q. Gong, T. Liu, Y. Deng, J.C. Chen, and G.Q. Chen. “Thioesterase II of Escherichia coli plays an important role in 3-hydroxydecanoic acid production.” Applied and Environmental Microbiology 70 (7): 3807-3813. (2004)