Clinical Trials

DO YOU HAVE TWO OR MORE MISSING BACK TEETH IN YOUR UPPER JAW?  

WOULD YOU LIKE TO REPLACE THEM WITH IMPLANTS?

If so, you may qualify to participate in a research study at the UCLA Periodontics and Implant Surgery Clinic to evaluate the effectiveness of implant thread design on implant stability during early healing. 

Purpose: The purpose of this study is to evaluate the stability of implants with two different thread designs over the early healing period (first 8 weeks) to determine whether thread design can enhance early implant stability. Both implant designs are already on the market and have proven to be safe and effective. 

HOW CAN I PARTICIPATE IN THIS STUDY?

Screening: If you are missing two or more upper back teeth, you will need to a comprehensive clinical and radiographic examination at UCLA Periodontics and Implant Surgery Clinic to determine your eligibility for participation in this study.

Requirements: In order to participate in this study, you must be 18 years old or older (male or female), generally in fair to good health and have enough bone for the placement of dental implant(s). You may not be eligible to participate if you have medical conditions or take medications that are known to impair healing or adversely affect bone health.

Expectations: If you take part in this study, the researcher(s) will ask you to make a total of (approximately) 11 visits to the UCLA Periodontics and Implant Surgery clinic. There will also be a need for 1 or more visits with a restorative dentist for planning fabrication of the implant crowns. A restorative dentist will be the one who makes and attaches replacement teeth (crown or other prosthesis) to the implants. 

Participants who meet the study criteria will receive patient education, comprehensive examination including radiographic imaging and implant planning as well as follow-up exams for data collection at no cost. The cost of implant placement will be discounted $400 off the current resident fee for implants. Participants will be asked to return for follow-up exams and data collection every week after implant placement for 8 weeks. Those who complete all follow-up visits will be compensated $100.00 cash. 

Summary: This research seeks individuals who are missing two or more upper back teeth with a desire to replace them with implants. The purpose of the clinical study is to assess the effectiveness of implant thread design on implant stability.

If you are interested and would like to be screened for participation in this implant study, please contact Principal Investigator, Dr. Perry Klokkevold, at the Periodontics and Implant Surgery Clinic: (310) 825-3795 or perio_implant@dentistry.ucla.edu


WOULD YOU LIKE TO TRY A NEW ELECTRONIC TOOTHBRUSH?

Researchers at the UCLA School of Dentistry are interested in your user experiences with a new electronic toothbrush system over a 4-week period. The system includes an Oral-B Genius 9000 Toothbrush, wearable wrist sensors, and a smart phone app to record your oral health behaviors.

In order to participate, you will be required to do the following during the duration of the study:

  • Allow your brushing and flossing details to be recorded

  • Carry a study-provided smart phone or if you have your own Android you can download the app instead.

  • Wear the provided wrist sensors

  • Respond to brief text message surveys

  • Visit our lab twice to undergo training and debriefing

Participants who complete the study could earn up to $140 + $12 for each lab visit and keep the Genius Toothbrush. Also if you use your personal Android phone then you will be given a $20 Data plan reimbursement for the month.

If you are interested in participating, or would like more information, please contact the study coordinator Amorette Castillo at 310-339-7162 or uclarobas@g.ucla.edu.

Principal Investigator: Dr. Vivek Shetty, UCLA School of Dentistry, research supported by the National Institutes of Health.


DO YOU HAVE A TOOTH IN THE FRONT OR MIDDLE OF YOUR UPPER OR LOWER JAW THAT NEEDS TO BE REMOVED?

You may qualify for a research study in the UCLA Dental Implant Center that will evaluate the long-term healing of dental implants. 

Purpose? To evaluate bone and gum healing after placement of a dental implant that is placed at the time of tooth removal as compared to a dental implant placed after healing of an extraction site.

Why? Implants are often placed at the time of tooth removal to decrease treatment time and allow for less surgical procedures. However, conventional dental implants are placed after the tooth is extracted and allowed to heal for several months. Very few direct comparative studies are available to see if there are any differences in these two treatment protocols. In this study, an FDA approved dental implant that is tapered to provide improved stability in the bone if placed at the time of tooth removal will be evaluated and compared to the same implant placed after the tooth extraction site has healed.

What to expect? Volunteers of 20 years of age or older, with overall good medical and dental health, and with at least one tooth in the front or middle of the upper or lower jaw that needs to be extracted may be eligible to participate in this study.

Consultation for research eligibility and if accepted, initial dental and implant examinations; including implant and crown placement. Procedure will be followed by 6 follow-up appointments, the last two at 4 and 5 years, to evaluate healing around the implant.

You may receive $300 payment for your involvement. You will also receive CT scans and 2 dental cleanings at no cost, and a discount on the implant and crown.

For information or to make an appointment contact Dr. Aghaloo in UCLA’s Dental Implant Center: (310) 206-6620, or visit us in UCLA’s Dental Implant Center, UCLA School of Dentistry, B0-129

MONDAY - FRIDAY, 8:00 a.m. - 5:00 p.m.

ALL APPOINTMENTS WILL BE CONDUCTED IN UCLA’s DENTAL IMPLANT CENTER

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