Wang Lab

Cun-Yu Wang, D.D.S., Ph.D. is a Professor and the Chair of the Division of Oral Biology and Medicine and the Associate Dean of Graduate Studies at the UCLA School of Dentistry. Dr. Wang is the first person to hold the Dr. No-Hee Park Endowed Chair in Dentistry.

Dr. Cun-Yu Wang is interested in three molecular signaling pathways: NF- k B, Wnt and HGF/c-Met. He made the landmark discovery that NF- k B, a transcription factor associated with inflammation and immune response, regulates cell survival and cell death. Recently, he showed that NF- k B plays a crucial role in the inhibition of bone formation in inflammatory and metabolic bone diseases. His work involves three major areas related to human oral and systemic diseases: 1) Molecular and epigenetic regulation of the invasive growth and metastasis of squamous cell carcinoma and breast cancer; 2) Molecular regulation of oral/systemic inflammation and host response; and 3) Molecular and genetic control of mesenchymal stem cell properties, bone formation and craniofacial regeneration.